Showing posts with label hemorrhage. Show all posts
Showing posts with label hemorrhage. Show all posts

Tuesday, December 11, 2012

Don’t Drink Heavily To Prevent Stroke!

Indulge in binge drinking is bad because the risk of developing heart disease becomes higher. But heavy drinkers of alcohol might also have other problems such as high blood pressure.
 
According to researchers from the University of Lille Nord de France, people who drank heavily might be getting a brain hemorrhage at a relatively early age. Hemorrhage is a type of stroke where ruptured blood vessels leak blood into the brain. Their findings were published on September 11, 2012 in journal ‘Neurology’.
 
They followed 540 patients with an average age of 71 who had hemorrhage. Among the participants, 137 people (or 25 percent) were heavy drinkers, which was defined as having 3 or more drinks a day or about 1.6 ounces per day of pure alcohol. These participants also underwent CT brain scans and their medical records were reviewed.
 
It was found that the heavy drinkers got brain hemorrhage typically at the age of 60, compared to the age of 74 among patients who were not heavy drinkers. Heavy drinkers were not only younger when they got their stroke they were also relatively healthy and less likely to have any history of heart disease, stroke or mini-stroke symptoms, compared to those who were not heavy drinkers.
 
Furthermore, the findings also discovered that when the stroke occurred in a deep part of the brain, heavy drinkers younger than 60 were more likely to die within 2 years than those who did not drink heavily. Even after discounting for factors like smoking habits, the heavy drinkers were twice as likely to die as compared to one-third of those who did not drink heavily.
 
In the study, heavy drinkers were found to have lower levels of certain substances that allow blood to clot, though those levels were still within the normal range.
 
The findings, however, could not prove that heavy drinking alone caused strokes at an earlier age. There might be other factors involved. For instance, heavy drinkers in the study were often smokers: 42 percent of them smoked compared to 12 percent of the other patients.
 
Since heavy drinking has long been considered a risk factor for strokes, this indicates that there are surely some reasons to believe that heavy drinking can be a problem.
 
Of course, this does not mean that drinking is strictly prohibited. People can still drink but moderation is the key. Remember this, excessive alcohol consumption is bad for the body in a number of ways.

Friday, December 11, 2009

What Can Plavix and Aspirin Do For Heart Disease Patients With AF?

A blood thinner, a common name for an anticoagulant agent, is a drug used to prevent formation of blood clots by hindering coagula. Blood thinner does not really thin the blood; it just prevents the blood from clotting. Doctors usually prescribe blood thinners to heart disease patients who are at risk for heart attack and stroke.

So far, anticoagulants such as warfarin and aspirin have been the only effective therapies in treating heart disease patients suffering from atrial fibrillation (AF). AF is a condition in which the heart's 2 upper chambers, the atria, quiver instead of beating effectively. This will raise the risk of blood clotting or pooling in the chambers that could eventually trigger a heart attack or stroke.

According to the American Heart Association (AHA), there are some 2.2 million Americans suffer from AF. These patients often need to be fitted with a pacemaker. Yet many of them cannot be treated with warfarin to stop blood clotting because warfarin increases the risk of an internal hemorrhage by up to 70 percent.

At the annual conference of the American College of Cardiology in Orlando on March 31, 2009, researchers from Ontario's McMaster University revealed that they managed to help AF patients cut the risk of heart attack and stroke by combining Plavix with aspirin.

Plavix is known under the generic name of clopidogrel. It is used to prevent the platelets in blood from coagulating and forming clots.

ACTIVE-A, a clinical trials involving 7,554 patients, aimed to determine whether the addition of clopidogrel to aspirin could reduce major vascular events and stroke in AF patients at an acceptable risk of increased hemorrhage. In the trials, the researchers showed that combination of Plavix and aspirin could help AF patients who are unable to take other blood thinners like warfarin.

The combination of clopidogrel and aspirin reduced major vascular events by 11 percent, including a 28 percent reduction in stroke and a 23 percent reduction in myocardial infarction (also known as heart attack), as found in the study.

It is believed that this is a new treatment for AF for the first time in 20 years.