Fructose is a simple sugar commonly used for sweetening drinks and foods. Short-term high fructose intake among young people is rather common. However, it appears that men and women have their own way of metabolizing high levels of fructose.
For men, such pattern of consumption will cause their blood triglycerides (fats) to increase and insulin resistance to decrease. This will also raise their risk for cardiovascular disease and Type-2 diabetes. On the other hand, women seem to get rid of the excess sugar load in a less harmful way.
In a study to evaluate the relationship between nutrition and metabolic disorders, researchers from Lausanne University School of Biology and Medicine in Switzerland enlisted 8 each of healthy, non-smoking men and women of normal weight and about 23 years of age to participate in 2 different 6-day diets separated by a 4-week wash-out period. The findings of the study were published in “Diabetes Care”
Not participated in sports or exercise, these men and women followed either the 'control' diet or the diet that included a lemon-flavored drink containing 3.5 grams of fructose.
The fructose load used for the study corresponded to several liters of sodas per day, which was considered quite large. 12 fasting metabolic parameters of the participants were tested the day after they completed each diet.
Fructose supplementation caused the men a significant increase in 11 of the 12 factors, including a 5 percent increase in fasting glucose and 71 percent increase in triglyceride levels. However, women had a significant increase in only 4 out of the 12 factors tested, and showed a 4 percent increase in fasting glucose and 16 percent increase in triglyceride levels.
As the current study only involved a very small number of participants, the researchers felt that further studies should be carried out to include a larger population so that gender differences in metabolic pathways could be accurately be identified and confirmed.
Meanwhile, the researchers also wonder if fructose may have effects that are more deleterious in individuals who are at high risk of metabolic disorders.
For men, such pattern of consumption will cause their blood triglycerides (fats) to increase and insulin resistance to decrease. This will also raise their risk for cardiovascular disease and Type-2 diabetes. On the other hand, women seem to get rid of the excess sugar load in a less harmful way.
In a study to evaluate the relationship between nutrition and metabolic disorders, researchers from Lausanne University School of Biology and Medicine in Switzerland enlisted 8 each of healthy, non-smoking men and women of normal weight and about 23 years of age to participate in 2 different 6-day diets separated by a 4-week wash-out period. The findings of the study were published in “Diabetes Care”
Not participated in sports or exercise, these men and women followed either the 'control' diet or the diet that included a lemon-flavored drink containing 3.5 grams of fructose.
The fructose load used for the study corresponded to several liters of sodas per day, which was considered quite large. 12 fasting metabolic parameters of the participants were tested the day after they completed each diet.
Fructose supplementation caused the men a significant increase in 11 of the 12 factors, including a 5 percent increase in fasting glucose and 71 percent increase in triglyceride levels. However, women had a significant increase in only 4 out of the 12 factors tested, and showed a 4 percent increase in fasting glucose and 16 percent increase in triglyceride levels.
As the current study only involved a very small number of participants, the researchers felt that further studies should be carried out to include a larger population so that gender differences in metabolic pathways could be accurately be identified and confirmed.
Meanwhile, the researchers also wonder if fructose may have effects that are more deleterious in individuals who are at high risk of metabolic disorders.
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